Nature CommunicationsPublished · 2024
Peer-reviewed methodology behind the gene–compound scoring that powers the intervention engine.
Wu et al.
Precision Longevity Intelligence
Decoding the biology of aging.
Built by the team behind the first inflammatory aging clock and the first epigenetic clock of intrinsic capacity.
Our thesis
Measure, track, and reroute aging before symptoms surface.
01
Tissue aging
Blood-biochemistry biomarkers
OrganAge™
Proactive Care
Reactive Medicine
02
Functional decline
Grip · VO₂max · vision · hearing
03
Symptoms & disease
Where accumulated decline finally surfaces
™Aging, measured system by system.
Nine physiological systems, scored from a single standard blood draw and grounded in clinical outcomes.
Cardiovascular
Immune
Metabolic
Digestive
Genitourinary
Respiratory
Nervous
Mental
MusculoskeletalHIPAA compliant · your data stays yours
Intervention
Your longevity, optimized.
Translate complex biological results into clearer priorities across food, movement, and supplements.
- Reads the genes behind your aging, from OrganAge™
- Scores food, movement, and supplements by how each acts on them
- Prioritizes the recommendations most relevant to optimizing your biology
Food
800+ foods scored against your genes.
Supplements
400 curated compounds.
Movement
Activity matched to your biology.
Powered byOptimAge™
The science
Published, peer-reviewed, independently validated.
The most precise, accurate, and clinically relevant measurement tool in the market.
Four axes of clinical validation
0.78–0.98
C-index · disease & mortality
ICC > 0.90
Test–retest reliability
9 systems
System-level resolution
OptimAge™
Every score is actionable
Nature MedicineUnder review
The methodology behind OrganAge™, at system-level resolution.
- Trained on 450,000+ UK Biobank participants
- Validated in an independent cohort
Fuentealba et al.
The team
The team building Cosmica.
Scientists and operators turning peer-reviewed aging research into products people can use.
Dr. Fei Wu
Chief Scientific Officer
Computational biology & multi-omics
Buck Institute
Dr. David Furman
Founder & Chief Executive Officer
Immunology & the biology of aging
Buck Institute · Stanford School of Medicine
Abhay Saini, MS
Co-founder & Chief Operating Officer
Operations & go-to-market
Buck Institute · UC Santa Barbara
Quantify your biology. Optimize your intervention. Prioritize your longevity.
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