

Accelerating Drug Discovery
for Longevity

Longevity Science & Space Biology
Spaceflight exposures alter the rate of cellular and organismal aging. Understanding these physiological changes in space has the potential to unlock new biomarkers and interventions that extend human health and lifespan on earth, as well as mitigate the risks of space exploration.
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Our Approach

We start with unbiased integrated multi-omic analysis of accelerated aging pathology
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Biomarkers of accelerated aging or rejuvenating mechanisms are confirmed through in-house and public datasets
We start with unbiased integrated multi-omic analysis of accelerated aging pathology
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Therapeutic targets are validated through pharmacologic intervention to evaluate efficacy
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Our Platform
Cosmica utilizes unbiased multi-scale biology coupled with machine learning algorithms to develop precision-based interventions aimed at extending human lifespan on earth and reducing health risks triggered by spaceflight exposures. Our platform leverages data generated from (1) human blood and organoids exposed to microgravity simulation and galactic radiation and (2) spaceflight, as well as (3) In vivo data from commercial and non-commercial crew members and onboard experiments from NASA, SpaceX and Axiom





Our Pipeline
Longevity-promoting drug discovery pipeline for promoting immune responses, improving cardiovascular health and reversing cognitive and metabolic decline.
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Our Story
Outer space is the final frontier for human exploration and presents a unique opportunity to explore human physiology. Indeed, exposure to microgravity and radiation in space accelerates the rate of cellular and organismal aging. Understanding these physiological changes in space has the potential to unlock new biomarkers and interventions that extend human health and lifespan on earth, as well as mitigate the risks of space exploration. The Buck Institute is a Center of Excellence in aging and longevity and has taken the first steps toward applying spaceflight research to uncover the biological mechanisms of human aging. Leading this effort is a team of world-class scientists from renowned academic institutions who've formed the first Consortium for Space Medicine and Human Longevity. To achieve maximum societal impact, the Buck has spun off Cosmica Inc. to pursue the translation of their core technology. To accomplish this mission, Cosmica was founded by a multidisciplinary team of thought-leaders in space medicine and longevity science unified under the mission to extend human longevity on earth and enable interplanetary human settlement.